One with the world? A new look at brains transformed by psychedelics.
Participants meditated inside an MRI tube, with and without psilocybin.
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Half of the participants ranked their session among the most meaningful experiences of their lives, and 24 put it in their personal top five. Stoliker and his colleagues started analyzing their brain scan data to find out why.
Measuring global functional connectivity—how much influence each patch of cortex exerts over the rest—the team found that, when participants had their eyes closed, sensory regions lost sway while associative regions gained. “It seems like the brain’s ability to construct reality, or imagination, or our associations, our beliefs, our sense of self—these faculties had more…
